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[Explanation] Patient Case CC: Flank Pain; Monotherapy IV for Pseudomonas & Enterococcus Sp. - #MEDIGRAM

Welcome to the #MEDIGRAM Patient Case: Chief Compliant Series. Short, concise patient cases to foster thought-provoking questions and to challenge you to ask questions! Make sure to by at the end of the week for explanations for the correct/incorrect answers.

 



 

🤖 [Explanation] Patient Case CC: Flank Pain, Fevers (Monotherapy IV Antibiotic for Pseudomonas and Enterococcus Sp?) - #MEDIGRAM



🔍 Enteroccocus species are inherently resistant against cephalosporin antibiotics, leaving us only piperacillin-tazobactam and meropenem. These are aminopenicillins and carbapenems, respectively. Both antibiotics would cover Pseudomonas.



😱 However, meropenem offers more broad coverage that includes ESBL bugs and has variable efficacy against Enteroccocus sp. They best MONOTHERAPY agent here would be PIPERACILLIN-TAZOBACTAM.



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