PHARMWYZE

Salicylate poisoning is a mixed-acid base disorder induced by uncoupling of mitochondrial oxidative phosphorylation and lactic acid...

Rattlesnakes, water moccasins, and copperheads are the more common species of concern in the United States. Rattlesnakes, water...

Physostigmine is a reversal agent for anticholinergic toxicities. Physostigmine is a reversal agent for anticholinergic toxicities. By...

Andexxa (andexanet alfa) binds to anti-Xa inhibitors like apixaban and rivoraxaban to temporarily reverse their anticoagulant effects....

Therapeutic doses of divalproex can still cause hyperammonemia. Therapeutic doses of divalproex can still cause hyperammonemia. An...

Intralipid emulsion is standard therapy for local-anesthetic systemic toxicities. Intralipid emulsion is standard therapy for...

Naloxone is one of the few true antidotes we have in medicine. Naloxone is one of the few true antidotes we have in medicine. It’s an...

Activated charcoal is most effective when given within 1 hour of toxic ingestions. Activated charcoal is most effective when given within...

Just because something is available over the counter, doesn’t necesarily mean it’s safe for complex patients and/or account for...

Muscle rigidity is a key characteristic of neuroleptic malignant syndrome (NMS). Muscle rigidity is a key characteristic of...

Maybe the devil’s lettuce is actually whats making you profusing vomit. Maybe the devil’s lettuce is actually whats making you profusing...

Patients on ketamine can develop iatrogenic laryngospasm and hypersalivation. Patients on ketamine can develop iatrogenic laryngospasm...

Wellbutrin was withdrawn from the market in 1986 due to high rates of seizures in a study on nondepressed bulimic patients. Wellbutrin...

Scorpion venom toxins inhibits inactivation of sodium channels, resulting in prolonged depolarization and autonomic excitation. Scorpion...

High-dose hydroxycobalamin (vitamin B12) has an FDA indication for cyanide toxicity, but has seen increased use for refractory...