Welcome to the #MEDSHED! Needing a brief, concise review of clinical pharmacotherapy and disease management? Direct links of reference to content discussed? Look no further than the #MEDSHED series based on infographics and carousel presentations!
👿 Heart Failure Guideline-Directed Medical Therapy (GDMT) - #MEDSHED
🔥 GDMT has proven to reduce mortality and morbidity in patients with HFrEF (EF < 40%)
Drug classes include RAAS-I/ARNI, BB, MRA, and SGLT2-I
🔮 RAAS-I / ANRI
Entresto (sacubitril-valsartan) has shown to reduce all-cause death by 16% vs ACE-i
May consider RAAS-I (lisinopril, losartan, etc), switch to ARNI when clinically stable
📭 Beta Blockers
Beta blockers have been associated with a reduction in all-cause mortality by ~35%
Specific BB: bisoprolol, carvedilol, and metoprolol succinate
🌐 MRA
Spirinolactone may reduce the incidence of cardiovascular death and heart-failure associated hospitalization
Initiate after RAAS-I/ARNI and BB
👀 SGLT2-I
Dapagliflozin and empagliflozin have shown to reduce all-cause death by 13% and hospitalizations by 25% in HFrEF with or without T2DM
Caution with volume status of patients on diuretics
🔍 Website: www.pharmwyze.com
Shop: www.pharmwyze.com/shop
Donate $5: www.pharmwyze.com//_paylink/AY78_L7r
Social Links: links.pharmwyze.com
DrugQueryInbox Request: https://pharmwyze.hopp.to/drugqueryinbox
Streaming Platforms: https://pharmwyze.hopp.to/podstreams
Patreon: www.patreon.com/pharmwyze
Paypal Donation: https://pharmwyze.hopp.to/paypaldonate
PHARMWYZE SITREP Newsletter: https://www.pharmwyze.com/sitrepnewsletter
Not medical advice. Educational purposes only. No relationships to report.
#emergency #ems #pharmacy #nursing #pharmacist #medicine #doctor #infection #toxicology #clinicalpearls #respiratory #antibiotics #neurology #acs #pharmwyze #codebluedebrief #overdose #medicalinsights #heartfailure #acs #cardiology #gdmt #diuretics #mortality #morbidity #clinicalpharmacy #medicalpearls
Comments