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Hypocalcemia, Lethal Triad, and Massive Transfusion Protocol | Resuscitation | #CodeBlueDebrief

 

 

Make sure to reel and deal those calcium salts during Massive Transfusion Protocol (MTP). Calcium salts are arguably the most important pharmacologic agent during MTP.


Hello there, Pharmers and Friends, Mark with PHARMWYZE. I'm a board certified emergency medicine pharmacist. I make clinical pharmacotherapy content on the social medias. Thanks for joining me on the Code Blue Debrief: A Clinical Pharmacotherapy YouTube & Podcast Series. We discuss emergency medicine and critical care pharmacology and disease state management.


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Not medical advice. Educational purposes only. No relationships to report.


 

References

Meneses E, Boneva D, McKenney M, Elkbuli A. Massive transfusion protocol in adult trauma population. Am J Emerg Med. 2020 Dec;38(12):2661-2666.

Wray JP, Bridwell RE, Schauer SG, Schakelford SA et al. The diamond of death: Hypocalcemia in trauma and resuscitation. Am J Emerg Med. 2021 Mar:41:104-109.

Helsoot D, Fitzgerald M, Lefering R et al. Trauma-induced disturbances in ionized calcium levels correlate parabolically with coagulopathy, transfusion, and mortality: a multicentre cohort analysis from the TraumaRegister DGU®.Crit Care. 2023 Jul 6;27(1):267.

Vasudeva M, Mathew JK, Groombridge C et al. Hypocalcemia in trauma patients: A systematic review. J Trauma Acute Care Surg. 2021 Feb; 90(2): 396–402.

Robinson A, Rech MA, DeChristopher PJ et al. Defining the optimal calcium repletion dosing in patients requiring activation of massive transfusion protocol. Am J Emerg Med. 2023 Aug:70:96-100.

Borowko R, Vignon PO, Lutz N. et al. The lethal triad of hemorrhage. Rev Infirm. 2021 Aug-Sep;70(273):16-18.

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